General Cell Lines and Cell Cultures
Eurofins Discoverx CHO-K1 GALR2 Gq Cell Line, 2 vials. (95-1010C2)
The GALR2 Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. galanin) based activation of GALR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses GALR2, a naturally Gq coupled GPCR. Upon activation of GALR2, the resulting calcium activity can be fluorescently assayed using the Calcium No WashPLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Heart: Ventricle (right), 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Eurofins Discoverx PathHunter CHO-K1 rGPR35 β-Arrestin Cell Line, 2 vials. (93-0887C2)
The PathHunter rGPR35 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. zaprinast) based activation of rGPR35 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rGPR35 and EA-tagged β-Arrestin-2. Activation of rGPR35 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Matched Pair - Frozen Tissue Section - Human Primary and Matched Metastatic Tumor (PM): Kidney, 5 x2 slides /PK
BioChain's tissue products are based on the sample repository network established following the ethical standard and IRB-approved procedures. During the collection, the excised tissues are immediately put into liquid nitrogen and then identified by a board-licensed pathologist. Patient demographic and disease related history data are available. Human frozen tissue section matched pair products include: Primary Pair (PP), Primary and Metastatic Pair (PM). PP consists of frozen tissue sections of primary tumor and its adjacent normal tissue; PM consists of frozen tissue sections of primary tumor and corresponding metastatic tumor. Frozen tissue sections in each pair are prepared from the same donor. This product line is ideal for localization of tumor-specific genes and tumor metastatic genes.
